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Estimation of Creatinine Clearance Rates

Do not use the eGFR for dose calculations of renally excreted drugs, it has not be validated for this use. Use Cockcroft and Gault equation (Calculator is available on the NSH Intranet - here. The eGFR result may deviate from the true value in extremes of body composition , age or dietary intake, or where there is rapid changing renal function.

Cockcroft-Gault
Formula
Age : years
Ideal Weight : kg
Serum Creatinine Concentration : micromol/L
N.B. - Serum Creatinine in micromol/L following PaLMS reporting changes (July 2005).

Estimated creatinine clearance (male) : mL/min
Estimated creatinine clearance (female) : mL/min

Estimated creatinine clearance
in men = (140 - age) x ideal weight
0.814 x [serum creatinine]
   
in women = 0.85 x creatinine clearance in men


Authorisation Stamp
Document Owner: - RNS Haematology Version: - 5 Document Number: - 003682620
Author: - Luke Coyle, Mary-Ann Saba, Georgina Brett Facility: - RNSH Authorised By: - Staff Haematologist (Dr Luke Coyle)
Email: - lcoyle Phone: - 992 67269 Last Modified: - 20-Jul-2005


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